Clinical Evidence

The science is settled. The gap is in delivery.

Digital health nudges are one of the most-studied interventions of the last decade. Piu Health personalizes the proven signal to each individual's condition, culture, and circumstance.

−0.4% HbA1c
Smartphone interventions reduce HbA1c
Lancet Digital Health2023

56 RCTs · 11,486 patients. Comparable to adding an oral agent — without the side effects. Daily digital engagement is now as strong as pharmacotherapy for early-stage management.

50% of Rx
Half of chronic meds are taken incorrectly
CDC MMWR2017

Timing and dose errors, prescriptions never filled, early discontinuation. $100–300B annual cost to US healthcare.

0% higher
Non-adherence drives hospital admissions
CDC Atlas of Heart Disease

Non-adherent vs. adherent chronic patients. Every 1% drop in BP medication adherence leads to 7.13 more cardiovascular deaths per 100K adults.

0% adults
Rank taste over health at mealtimes
Pew ResearchMay 2025

Cultural food preferences drive long-term adherence — but no major platform speaks to North Indian vegetarian, South Asian, halal, or Latino diets.

The Burden

Seven conditions. One platform.

Piu Health covers the top chronic conditions driving 90% of US healthcare spend — in a single white-label platform.

Hypertension
#1 prevalence · only 21% controlled
$131B/yr
Obesity
Gateway to diabetes, heart disease, cancer
$173B/yr
Diabetes (T2D)
Leading cause of blindness and amputation
$327B/yr
Arthritis
Projected 78M by 2040 · 44% have activity limits
$304B/yr
Heart Disease
#1 cause of US death · largely preventable
$240B+/yr
COPD
Under-diagnosed · medication adherence critical
$32B/yr
CKD
90% unaware until late stage
$87B/yr
ConditionPrevalenceUS AdultsAnnual CostKey Signal
Hypertension48%122M$131B/yr#1 prevalence · only 21% controlled
Obesity40%100M+$173B/yrGateway to diabetes, heart disease, cancer
Diabetes (T2D)11%37M$327B/yrLeading cause of blindness and amputation
Arthritis28%67M$304B/yrProjected 78M by 2040 · 44% have activity limits
Heart Disease$240B+/yr#1 cause of US death · largely preventable
COPD6%16M$32B/yrUnder-diagnosed · medication adherence critical
CKD15%37M$87B/yr90% unaware until late stage

Sources: CDC BRFSS 2023 · AHA 2024 · AHRQ · CMS NHE 2024